Maturation signatures of conventional dendritic cell subtypes in COVID‐19 suggest direct viral sensing

Growing evidence suggests that conventional dendritic cells (cDCs) undergo aberrant maturation in COVID‐19, which negatively affects T‐cell activation. The presence of effector T cells in patients with mild disease and dysfunctional T cells in severely ill patients suggests that adequate T‐cell resp...

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Detalles Bibliográficos
Autores principales: Marongiu, Laura, Protti, Giulia, Facchini, Fabio A., Valache, Mihai, Mingozzi, Francesca, Ranzani, Valeria, Putignano, Anna Rita, Salviati, Lorenzo, Bevilacqua, Valeria, Curti, Serena, Crosti, Mariacristina, Sarnicola, Maria Lucia, D'Angiò, Mariella, Bettini, Laura Rachele, Biondi, Andrea, Nespoli, Luca, Tamini, Nicolò, Clementi, Nicola, Mancini, Nicasio, Abrignani, Sergio, Spreafico, Roberto, Granucci, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Immunity to infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420462/
https://www.ncbi.nlm.nih.gov/pubmed/34333764
http://dx.doi.org/10.1002/eji.202149298

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