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Maturation signatures of conventional dendritic cell subtypes in COVID‐19 suggest direct viral sensing
Growing evidence suggests that conventional dendritic cells (cDCs) undergo aberrant maturation in COVID‐19, which negatively affects T‐cell activation. The presence of effector T cells in patients with mild disease and dysfunctional T cells in severely ill patients suggests that adequate T‐cell resp...
Autores principales: | Marongiu, Laura, Protti, Giulia, Facchini, Fabio A., Valache, Mihai, Mingozzi, Francesca, Ranzani, Valeria, Putignano, Anna Rita, Salviati, Lorenzo, Bevilacqua, Valeria, Curti, Serena, Crosti, Mariacristina, Sarnicola, Maria Lucia, D'Angiò, Mariella, Bettini, Laura Rachele, Biondi, Andrea, Nespoli, Luca, Tamini, Nicolò, Clementi, Nicola, Mancini, Nicasio, Abrignani, Sergio, Spreafico, Roberto, Granucci, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420462/ https://www.ncbi.nlm.nih.gov/pubmed/34333764 http://dx.doi.org/10.1002/eji.202149298 |
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