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Specific detection of memory T‐cells in COVID‐19 patients using standardized whole‐blood Interferon gammarelease assay
Antigen‐specific T‐cells are essential for protective immunity against SARS‐CoV‐2. We set up a semi‐automated whole‐blood Interferon‐gamma release assay (WB IGRA) to monitor the T‐cell response after stimulation with SARS‐CoV‐2 peptide pools. We report that the WB IGRA is complementary to serologica...
| Autores principales: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420580/ https://www.ncbi.nlm.nih.gov/pubmed/34387859 http://dx.doi.org/10.1002/eji.202149296 |
| _version_ | 1783748922622083072 |
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| author | Mouton, William Compagnon, Christelle Saker, Kahina Daniel, Soizic Djebali, Sophia Lacoux, Xavier Pozzetto, Bruno Oriol, Guy Laubreton, Daphné Prieux, Margaux Fassier, Jean‐Baptiste Guibert, Nicolas Massardier‐Pilonchéry, Amélie Alfaiate, Dulce Berthier, Franck Walzer, Thierry Marvel, Jacqueline Brengel‐Pesce, Karen Trouiller‐Assant, Sophie |
| author_facet | Mouton, William Compagnon, Christelle Saker, Kahina Daniel, Soizic Djebali, Sophia Lacoux, Xavier Pozzetto, Bruno Oriol, Guy Laubreton, Daphné Prieux, Margaux Fassier, Jean‐Baptiste Guibert, Nicolas Massardier‐Pilonchéry, Amélie Alfaiate, Dulce Berthier, Franck Walzer, Thierry Marvel, Jacqueline Brengel‐Pesce, Karen Trouiller‐Assant, Sophie |
| author_sort | Mouton, William |
| collection | PubMed |
| description | Antigen‐specific T‐cells are essential for protective immunity against SARS‐CoV‐2. We set up a semi‐automated whole‐blood Interferon‐gamma release assay (WB IGRA) to monitor the T‐cell response after stimulation with SARS‐CoV‐2 peptide pools. We report that the WB IGRA is complementary to serological assays to assess SARS‐CoV‐2 immunity. [Image: see text] |
| format | Online Article Text |
| id | pubmed-8420580 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-84205802021-09-07 Specific detection of memory T‐cells in COVID‐19 patients using standardized whole‐blood Interferon gammarelease assay Mouton, William Compagnon, Christelle Saker, Kahina Daniel, Soizic Djebali, Sophia Lacoux, Xavier Pozzetto, Bruno Oriol, Guy Laubreton, Daphné Prieux, Margaux Fassier, Jean‐Baptiste Guibert, Nicolas Massardier‐Pilonchéry, Amélie Alfaiate, Dulce Berthier, Franck Walzer, Thierry Marvel, Jacqueline Brengel‐Pesce, Karen Trouiller‐Assant, Sophie Eur J Immunol Letters to the Editor Antigen‐specific T‐cells are essential for protective immunity against SARS‐CoV‐2. We set up a semi‐automated whole‐blood Interferon‐gamma release assay (WB IGRA) to monitor the T‐cell response after stimulation with SARS‐CoV‐2 peptide pools. We report that the WB IGRA is complementary to serological assays to assess SARS‐CoV‐2 immunity. [Image: see text] John Wiley and Sons Inc. 2021-09-06 2021-12 /pmc/articles/PMC8420580/ /pubmed/34387859 http://dx.doi.org/10.1002/eji.202149296 Text en © 2021 The Authors. European Journal of Immunology published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
| spellingShingle | Letters to the Editor Mouton, William Compagnon, Christelle Saker, Kahina Daniel, Soizic Djebali, Sophia Lacoux, Xavier Pozzetto, Bruno Oriol, Guy Laubreton, Daphné Prieux, Margaux Fassier, Jean‐Baptiste Guibert, Nicolas Massardier‐Pilonchéry, Amélie Alfaiate, Dulce Berthier, Franck Walzer, Thierry Marvel, Jacqueline Brengel‐Pesce, Karen Trouiller‐Assant, Sophie Specific detection of memory T‐cells in COVID‐19 patients using standardized whole‐blood Interferon gammarelease assay |
| title | Specific detection of memory T‐cells in COVID‐19 patients using standardized whole‐blood Interferon gammarelease assay |
| title_full | Specific detection of memory T‐cells in COVID‐19 patients using standardized whole‐blood Interferon gammarelease assay |
| title_fullStr | Specific detection of memory T‐cells in COVID‐19 patients using standardized whole‐blood Interferon gammarelease assay |
| title_full_unstemmed | Specific detection of memory T‐cells in COVID‐19 patients using standardized whole‐blood Interferon gammarelease assay |
| title_short | Specific detection of memory T‐cells in COVID‐19 patients using standardized whole‐blood Interferon gammarelease assay |
| title_sort | specific detection of memory t‐cells in covid‐19 patients using standardized whole‐blood interferon gammarelease assay |
| topic | Letters to the Editor |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420580/ https://www.ncbi.nlm.nih.gov/pubmed/34387859 http://dx.doi.org/10.1002/eji.202149296 |
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