Protocol for a multicentre, randomised, parallel-control, superiority trial comparing administration of clotting factor concentrates with a standard massive haemorrhage protocol in severely bleeding trauma patients: the FiiRST 2 trial (a 2020 EAST multicentre trial)

INTRODUCTION: Acute traumatic coagulopathy (ATC) in bleeding trauma patients increase in-hospital mortality. Fibrinogen concentrate (FC) and prothrombin complex concentrate (PCC) are two purified concentrates of clotting factors that have been used to treat ATC. However, there is a knowledge gap on...

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Detalles Bibliográficos
Autores principales: da Luz, Luis Teodoro, Callum, Jeannie, Beckett, Andrew, Hucke, Hans-Peter, Carroll, Jo, Grewal, Deep, Schwartz, Bruce, Peng, Henry, Engels, Paul T, Parry, Neil, Petrosoniak, Andrew, Tien, Homer, Nathens, Avery B, Scales, Damon, Karkouti, Keyvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Emergency Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420689/
https://www.ncbi.nlm.nih.gov/pubmed/34479938
http://dx.doi.org/10.1136/bmjopen-2021-051003

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