Cargando…

Structural insights into the substrate-binding proteins Mce1A and Mce4A from Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb), which is responsible for more than a million deaths annually, uses lipids as the source of carbon and energy for its survival in the latent phase of infection. Mtb cannot synthesize all of the lipid molecules required for its growth and pathogenicity. Therefore, it...

Descripción completa

Detalles Bibliográficos
Autores principales:	Asthana, Pooja, Singh, Dhirendra, Pedersen, Jan Skov, Hynönen, Mikko J., Sulu, Ramita, Murthy, Abhinandan V., Laitaoja, Mikko, Jänis, Janne, Riley, Lee W., Venkatesan, Rajaram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2021
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420772/ https://www.ncbi.nlm.nih.gov/pubmed/34584737 http://dx.doi.org/10.1107/S2052252521006199

Ejemplares similares

MceG stabilizes the Mce1 and Mce4 transporters in Mycobacterium tuberculosis
por: Fieweger, Rachael A., et al.
Publicado: (2023)

Study of the role of Mce3R on the transcription of mce genes of Mycobacterium tuberculosis
por: Santangelo, María P, et al.
Publicado: (2008)

Analysis of expression profile of mce operon genes (mce1, mce2, mce3 operon) in different Mycobacterium tuberculosis isolates at different growth phases
por: Singh, Pratibha, et al.
Publicado: (2016)

Study of the in vivo role of Mce2R, the transcriptional regulator of mce2 operon in Mycobacterium tuberculosis
por: Forrellad, Marina Andrea, et al.
Publicado: (2013)

Single nucleotide polymorphism in the genes of mce1 and mce4 operons of Mycobacterium tuberculosis: analysis of clinical isolates and standard reference strains
por: Pasricha, Rashmi, et al.
Publicado: (2011)

Mycobacterium tuberculosis Uses Mce Proteins to Interfere With Host Cell Signaling
por: Fenn, Katherine, et al.
Publicado: (2020)

A phylogenomic analysis of the Actinomycetales mce operons
por: Casali, Nicola, et al.
Publicado: (2007)

Characterization of Mce4A protein of Mycobacterium tuberculosis: role in invasion and survival
por: Saini, Neeraj Kumar, et al.
Publicado: (2008)

The Actinobacterial mce Operon: Structure and Functions
por: Zaychikova, M. V., et al.
Publicado: (2020)

Structure of an endogenous mycobacterial MCE lipid transporter
por: Chen, James, et al.
Publicado: (2023)

Modulation of Transcriptional and Inflammatory Responses in Murine Macrophages by the Mycobacterium tuberculosis Mammalian Cell Entry (Mce) 1 Complex
por: Stavrum, Ruth, et al.
Publicado: (2011)

Correction: Modulation of Transcriptional and Inflammatory Responses in Murine Macrophages by the Mycobacterium tuberculosis Mammalian Cell Entry (Mce) 1 Complex
por: Stavrum, Ruth, et al.
Publicado: (2011)

Mce1C and Mce1D facilitate N. farcinica invasion of host cells and suppress immune responses by inhibiting innate signaling pathways
por: Ji, Xingzhao, et al.
Publicado: (2020)

Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H α(2)β(2) tetramer
por: Murthy, Abhinandan V., et al.
Publicado: (2022)

$MCE_{Q}$ - numerical code for inclusive lepton flux calculations
por: Fedynitch, Anatoli, et al.
Publicado: (2016)

Functional analysis of an intergenic non-coding sequence within mce1 operon of M.tuberculosis
por: Joon, Monika, et al.
Publicado: (2010)

A conserved membrane protein negatively regulates Mce1 complexes in mycobacteria
por: Chen, Yushu, et al.
Publicado: (2023)

CLONING AND EXPRESSION OF MCE1A GENE FROM MYCOBACTERIUM TUBERCULOSIS BEIJING AND H37RV STRAIN FOR VACCINE CANDIDATE DEVELOPMENT
por: Indriarini, Desi, et al.
Publicado: (2018)

Novel recombinant Mce-truncated protein based ELISA for the diagnosis of Mycobacterium avium subsp. paratuberculosis infection in domestic livestock
por: Hemati, Zahra, et al.
Publicado: (2020)

Mce3R Stress-Resistance Pathway Is Vulnerable to Small-Molecule Targeting That Improves Tuberculosis Drug Activities
por: Yang, Xinxin, et al.
Publicado: (2019)

Differential Host Pro-Inflammatory Response to Mycobacterial Cell Wall Lipids Regulated by the Mce1 Operon
por: Petrilli, Jéssica D., et al.
Publicado: (2020)

Assessment of the Immune Responses Induced in Cattle after Inoculation of a Mycobacterium bovis Strain Deleted in Two mce2 Genes
por: Blanco, Federico Carlos, et al.
Publicado: (2012)

Immuno-reactivity evaluation of Mce-truncated subunit candidate vaccine against Mycobacterium avium subspecies paratuberculosis challenge in the goat models
por: Haghkhah, Masoud, et al.
Publicado: (2023)

MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis
por: Isom, Georgia L., et al.
Publicado: (2017)

Regulation of Paracellular Fluxes of Amino Acids by Claudin-8 in Normal Mouse Intestinal MCE301 Cells
por: Okamoto, Ema, et al.
Publicado: (2023)

Identification of Antigens Specific to Non-Tuberculous Mycobacteria: The Mce Family of Proteins as a Target of T Cell Immune Responses
por: Checkley, Anna M., et al.
Publicado: (2011)

Draft Genome Sequence of Taylorella equigenitalis Strain MCE529, Isolated from a Belgian Warmblood Horse
por: Hébert, Laurent, et al.
Publicado: (2014)

Epitope-Based Vaccine Designing of Nocardia asteroides Targeting the Virulence Factor Mce-Family Protein by Immunoinformatics Approach
por: Patra, Prasanta, et al.
Publicado: (2019)

Cyanidin Increases the Expression of Mg(2+) Transport Carriers Mediated by the Activation of PPARα in Colonic Epithelial MCE301 Cells
por: Takashina, Yui, et al.
Publicado: (2019)

Cloning, Expression, Invasion, and Immunological Reactivity of a Mammalian Cell Entry Protein Encoded by the mce1 Operon of Nocardia farcinica
por: Ji, Xingzhao, et al.
Publicado: (2017)

ELISA-based assay of immunoglobulin G antibodies against mammalian cell entry 1A (Mce1A) protein: a novel diagnostic approach for leprosy
por: Lima, Filipe R, et al.
Publicado: (2017)

Sunscreens with the New MCE Filter Cover the Whole UV Spectrum: Improved UVA1 Photoprotection In Vitro and in a Randomized Controlled Trial
por: Marionnet, Claire, et al.
Publicado: (2021)

Serological testing for Hansen’s disease diagnosis: Clinical significance and performance of IgA, IgM, and IgG antibodies against Mce1A protein
por: Lima, Filipe Rocha, et al.
Publicado: (2023)

Selection of the final solid waste disposal site in the Bolgatanga municipality of Ghana using analytical hierarchy process (AHP) and multi-criteria evaluation (MCE)
por: Ampofo, Steve, et al.
Publicado: (2023)

Serological Immunoassay for Hansen’s Disease Diagnosis and Monitoring Treatment: Anti-Mce1A Antibody Response Among Hansen’s Disease Patients and Their Household Contacts in Northeastern Brazil
por: Lima, Filipe Rocha, et al.
Publicado: (2022)

Bifunctional Avidin with Covalently Modifiable Ligand Binding Site
por: Leppiniemi, Jenni, et al.
Publicado: (2011)

Characterization of porphobilinogen deaminase mutants reveals that arginine-173 is crucial for polypyrrole elongation mechanism
por: Bustad, Helene J., et al.
Publicado: (2021)

Structural and functional insights into the unique CBS–CP12 fusion protein family in cyanobacteria
por: Hackenberg, Claudia, et al.
Publicado: (2018)

Biochemical and Biophysical Characterization of Carbonic Anhydrase VI from Human Milk and Saliva
por: Yrjänäinen, Alma, et al.
Publicado: (2022)

Characterisation of a common hotspot variant in acute intermittent porphyria sheds light on the mechanism of hydroxymethylbilane synthase function
por: Christie, Marthe S., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_u7elmfbprh6n58bc113bmknt0g