Pro-inflammatory β cell small extracellular vesicles induce β cell failure through activation of the CXCL10/CXCR3 axis in diabetes

Coordinated communication among pancreatic islet cells is necessary for maintenance of glucose homeostasis. In diabetes, chronic exposure to pro-inflammatory cytokines has been shown to perturb β cell communication and function. Compelling evidence has implicated extracellular vesicles (EVs) in modu...

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Detalles Bibliográficos
Autores principales: Javeed, Naureen, Her, Tracy K., Brown, Matthew R., Vanderboom, Patrick, Rakshit, Kuntol, Egan, Aoife M., Vella, Adrian, Lanza, Ian, Matveyenko, Aleksey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420815/
https://www.ncbi.nlm.nih.gov/pubmed/34433033
http://dx.doi.org/10.1016/j.celrep.2021.109613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420815/
https://www.ncbi.nlm.nih.gov/pubmed/34433033
http://dx.doi.org/10.1016/j.celrep.2021.109613

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