Symptomatic SARS-COV-2 reinfection: healthcare workers and immunosuppressed individuals at high risk

BACKGROUND: Knowledge regarding factors predicting the SARS-COV-2 reinfection risk is scarce and it has major implications in public health policies. We aimed to identify factors associated with the risk of symptomatic SARS-COV-2 reinfection. METHODS: We conducted a nationwide retrospective cohort s...

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Autores principales: Murillo-Zamora, Efrén, Trujillo, Xóchitl, Huerta, Miguel, Ríos-Silva, Mónica, Aguilar-Sollano, Felipe, Mendoza-Cano, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420845/
https://www.ncbi.nlm.nih.gov/pubmed/34488661
http://dx.doi.org/10.1186/s12879-021-06643-1
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author Murillo-Zamora, Efrén
Trujillo, Xóchitl
Huerta, Miguel
Ríos-Silva, Mónica
Aguilar-Sollano, Felipe
Mendoza-Cano, Oliver
author_facet Murillo-Zamora, Efrén
Trujillo, Xóchitl
Huerta, Miguel
Ríos-Silva, Mónica
Aguilar-Sollano, Felipe
Mendoza-Cano, Oliver
author_sort Murillo-Zamora, Efrén
collection PubMed
description BACKGROUND: Knowledge regarding factors predicting the SARS-COV-2 reinfection risk is scarce and it has major implications in public health policies. We aimed to identify factors associated with the risk of symptomatic SARS-COV-2 reinfection. METHODS: We conducted a nationwide retrospective cohort study and 99,993 confirmed cases of COVID-19 were analyzed. RESULTS: The overall risk of reinfection (28 or more elapsed days between both episodes onset) was 0.21% (incidence density, 2.5 reinfections per 100,000 person-days) and older subjects and those with the mild primary disease were at reduced risk of the event. Healthcare workers and immunosuppressed or renal patients had at greater risk of SARS-COV-2 reinfection. CONCLUSIONS: If replicated in other populations, these results may be useful to prioritize efforts focusing on the reduction of SARS-COV-2 spread and the related burden.
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spelling pubmed-84208452021-09-07 Symptomatic SARS-COV-2 reinfection: healthcare workers and immunosuppressed individuals at high risk Murillo-Zamora, Efrén Trujillo, Xóchitl Huerta, Miguel Ríos-Silva, Mónica Aguilar-Sollano, Felipe Mendoza-Cano, Oliver BMC Infect Dis Research BACKGROUND: Knowledge regarding factors predicting the SARS-COV-2 reinfection risk is scarce and it has major implications in public health policies. We aimed to identify factors associated with the risk of symptomatic SARS-COV-2 reinfection. METHODS: We conducted a nationwide retrospective cohort study and 99,993 confirmed cases of COVID-19 were analyzed. RESULTS: The overall risk of reinfection (28 or more elapsed days between both episodes onset) was 0.21% (incidence density, 2.5 reinfections per 100,000 person-days) and older subjects and those with the mild primary disease were at reduced risk of the event. Healthcare workers and immunosuppressed or renal patients had at greater risk of SARS-COV-2 reinfection. CONCLUSIONS: If replicated in other populations, these results may be useful to prioritize efforts focusing on the reduction of SARS-COV-2 spread and the related burden. BioMed Central 2021-09-06 /pmc/articles/PMC8420845/ /pubmed/34488661 http://dx.doi.org/10.1186/s12879-021-06643-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Murillo-Zamora, Efrén
Trujillo, Xóchitl
Huerta, Miguel
Ríos-Silva, Mónica
Aguilar-Sollano, Felipe
Mendoza-Cano, Oliver
Symptomatic SARS-COV-2 reinfection: healthcare workers and immunosuppressed individuals at high risk
title Symptomatic SARS-COV-2 reinfection: healthcare workers and immunosuppressed individuals at high risk
title_full Symptomatic SARS-COV-2 reinfection: healthcare workers and immunosuppressed individuals at high risk
title_fullStr Symptomatic SARS-COV-2 reinfection: healthcare workers and immunosuppressed individuals at high risk
title_full_unstemmed Symptomatic SARS-COV-2 reinfection: healthcare workers and immunosuppressed individuals at high risk
title_short Symptomatic SARS-COV-2 reinfection: healthcare workers and immunosuppressed individuals at high risk
title_sort symptomatic sars-cov-2 reinfection: healthcare workers and immunosuppressed individuals at high risk
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420845/
https://www.ncbi.nlm.nih.gov/pubmed/34488661
http://dx.doi.org/10.1186/s12879-021-06643-1
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