Cargando…

Secondary Structure of Human De Novo Evolved Gene Product NCYM Analyzed by Vacuum-Ultraviolet Circular Dichroism

NCYM, a cis-antisense gene of MYCN, encodes a Homininae-specific protein that promotes the aggressiveness of human tumors. Newly evolved genes from non-genic regions are known as de novo genes, and NCYM was the first de novo gene whose oncogenic functions were validated in vivo. Targeting NCYM using...

Descripción completa

Detalles Bibliográficos
Autores principales: Matsuo, Tatsuhito, Nakatani, Kazuma, Setoguchi, Taiki, Matsuo, Koichi, Tamada, Taro, Suenaga, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420857/
https://www.ncbi.nlm.nih.gov/pubmed/34497756
http://dx.doi.org/10.3389/fonc.2021.688852