Cargando…
Secondary Structure of Human De Novo Evolved Gene Product NCYM Analyzed by Vacuum-Ultraviolet Circular Dichroism
NCYM, a cis-antisense gene of MYCN, encodes a Homininae-specific protein that promotes the aggressiveness of human tumors. Newly evolved genes from non-genic regions are known as de novo genes, and NCYM was the first de novo gene whose oncogenic functions were validated in vivo. Targeting NCYM using...
Autores principales: | Matsuo, Tatsuhito, Nakatani, Kazuma, Setoguchi, Taiki, Matsuo, Koichi, Tamada, Taro, Suenaga, Yusuke |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420857/ https://www.ncbi.nlm.nih.gov/pubmed/34497756 http://dx.doi.org/10.3389/fonc.2021.688852 |
Ejemplares similares
-
Assignment of Absolute Configuration of Bromoallenes by Vacuum-Ultraviolet Circular Dichroism (VUVCD)
por: Umezawa, Taiki, et al.
Publicado: (2021) -
Synchrotron-radiation vacuum-ultraviolet circular dichroism spectroscopy in structural biology: an overview
por: Gekko, Kunihiko
Publicado: (2019) -
NCYM, a Cis-Antisense Gene of MYCN, Encodes a De Novo Evolved Protein That Inhibits GSK3β Resulting in the Stabilization of MYCN in Human Neuroblastomas
por: Suenaga, Yusuke, et al.
Publicado: (2014) -
Functional interplay between MYCN, NCYM, and OCT4 promotes aggressiveness of human neuroblastomas
por: Kaneko, Yoshiki, et al.
Publicado: (2015) -
Near-Ultraviolet Circular Dichroism and Two-Dimensional Spectroscopy of Polypeptides
por: Segatta, Francesco, et al.
Publicado: (2021)