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LR Hunting: A Random Forest Based Cell–Cell Interaction Discovery Method for Single-Cell Gene Expression Data

Cell–cell interactions (CCIs) and cell–cell communication (CCC) are critical for maintaining complex biological systems. The availability of single-cell RNA sequencing (scRNA-seq) data opens new avenues for deciphering CCIs and CCCs through identifying ligand-receptor (LR) gene interactions between...

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Detalles Bibliográficos
Autores principales: Lu, Min, Sha, Yifan, Silva, Tiago C., Colaprico, Antonio, Sun, Xiaodian, Ban, Yuguang, Wang, Lily, Lehmann, Brian D., Chen, X. Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420858/
https://www.ncbi.nlm.nih.gov/pubmed/34497635
http://dx.doi.org/10.3389/fgene.2021.708835