Cargando…

N6-Methyladenosine Writer Gene ZC3H13 Predicts Immune Phenotype and Therapeutic Opportunities in Kidney Renal Clear Cell Carcinoma

BACKGROUND: Although the RNA modification N6-methyladenosine ZC3H13 has been found to play vital regulatory roles in many types of cancers, its role in predicting the tumor immune microenvironment (TME) and response to immune checkpoint blockade (ICB) in kidney renal clear cell carcinoma (KIRC) rema...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Tao, Duan, Hongxiang, Chen, Jinbo, Liu, Jinhui, Othmane, Belaydi, Hu, Jiao, Li, Huihuang, Zu, Xiongbing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420859/ https://www.ncbi.nlm.nih.gov/pubmed/34497769 http://dx.doi.org/10.3389/fonc.2021.718644

Ejemplares similares

RNA Modification of N6-Methyladenosine Predicts Immune Phenotypes and Therapeutic Opportunities in Kidney Renal Clear Cell Carcinoma
por: Li, Huihuang, et al.
Publicado: (2021)

A Poliovirus Receptor (CD155)-Related Risk Signature Predicts the Prognosis of Bladder Cancer
por: Luo, Cong, et al.
Publicado: (2021)

Effects of Fibrin Clot Inhibitors and Statins on the Intravesical Bacille Calmette–Guérin Therapy for Bladder Cancer: A Systematic Review and Meta-Analysis
por: Cai, Zhiyong, et al.
Publicado: (2021)

Emerging Biomarkers for Predicting Bladder Cancer Lymph Node Metastasis
por: Zhang, Chunyu, et al.
Publicado: (2021)

N(6)-Methyladenosine in Cancer Immunotherapy: An Undervalued Therapeutic Target
por: Quan, Chao, et al.
Publicado: (2021)

5mC regulator-mediated molecular subtypes depict the hallmarks of the tumor microenvironment and guide precision medicine in bladder cancer
por: Hu, Jiao, et al.
Publicado: (2021)

m(6)A-induced lncDBET promotes the malignant progression of bladder cancer through FABP5-mediated lipid metabolism
por: Liu, Peihua, et al.
Publicado: (2022)

Analysis of N6-Methyladenosine Methyltransferase Reveals METTL14 and ZC3H13 as Tumor Suppressor Genes in Breast Cancer
por: Gong, Peng-Ju, et al.
Publicado: (2020)

miR-616-5p Promotes Invasion and Migration of Bladder Cancer via Downregulating NR2C2 Expression
por: Ren, Wenbiao, et al.
Publicado: (2021)

A Novel TGF-β Risk Score Predicts the Clinical Outcomes and Tumour Microenvironment Phenotypes in Bladder Cancer
por: Liu, Zhi, et al.
Publicado: (2021)

Filling the gaps in the research about second primary malignancies after bladder cancer: Focus on race and histology
por: Othmane, Belaydi, et al.
Publicado: (2022)

Recurrence factors in patients with Keratinizing squamous metaplasia of the bladder after surgical management: a single-center retrospective study
por: Yi, Zhenglin, et al.
Publicado: (2021)

YTHDF1 Is a Potential Pan-Cancer Biomarker for Prognosis and Immunotherapy
por: Hu, Jian, et al.
Publicado: (2021)

A Robust Hypoxia Risk Score Predicts the Clinical Outcomes and Tumor Microenvironment Immune Characters in Bladder Cancer
por: Liu, Zhi, et al.
Publicado: (2021)

Cuproptosis depicts tumor microenvironment phenotypes and predicts precision immunotherapy and prognosis in bladder carcinoma
por: Li, Huihuang, et al.
Publicado: (2022)

Siglec15 shapes a non-inflamed tumor microenvironment and predicts the molecular subtype in bladder cancer
por: Hu, Jiao, et al.
Publicado: (2021)

N(6)-methyladenosine modification of CENPK mRNA by ZC3H13 promotes cervical cancer stemness and chemoresistance
por: Lin, Xian, et al.
Publicado: (2022)

Clinicopathological characteristics and survival outcomes for testicular choriocarcinoma: a population-based study
por: Li, Huihuang, et al.
Publicado: (2021)

Adjuvant chemotherapy in patients with locally advanced bladder cancer after neoadjuvant chemotherapy and radical cystectomy: a systematic review and pooled analysis
por: Cai, Zhiyong, et al.
Publicado: (2021)

Cuproptosis-related modification patterns depict the tumor microenvironment, precision immunotherapy, and prognosis of kidney renal clear cell carcinoma
por: Cai, Zhiyong, et al.
Publicado: (2022)

N6-methyladenosine methylation-related genes YTHDF2, METTL3, and ZC3H13 predict the prognosis of hepatocellular carcinoma patients
por: Wang, Yun, et al.
Publicado: (2022)

PMEPA1 Is a Prognostic Biomarker That Correlates With Cell Malignancy and the Tumor Microenvironment in Bladder Cancer
por: Qiu, Dongxu, et al.
Publicado: (2021)

Efficacy of Intra-Arterial Plus Intravesical Chemotherapy for High-Risk Non-Muscle-Invasive Bladder Cancer: A Pooled Analysis
por: Cheng, Chunliang, et al.
Publicado: (2021)

Understanding the roles of N(6)-methyladenosine writers, readers and erasers in breast cancer
por: Fang, Runping, et al.
Publicado: (2021)

RNA N (6)-Methyladenosine in Cancer Metastasis: Roles, Mechanisms, and Applications
por: Dang, Qin, et al.
Publicado: (2021)

Identification and validation of the N6-methyladenosine RNA methylation regulator ZC3H13 as a novel prognostic marker and potential target for hepatocellular carcinoma
por: Wu, Shuang, et al.
Publicado: (2022)

Primary mucinous adenocarcinoma of the renal pelvis misdiagnosed as calculous pyonephrosis: a case report and literature review
por: Li, Huihuang, et al.
Publicado: (2020)

The Emerging Role of RNA N6-Methyladenosine Modification in Pancreatic Cancer
por: Hu, Xiaoge, et al.
Publicado: (2022)

Effect of neoadjuvant chemotherapy on locally advanced upper tract urothelial carcinoma: a pooled analysis
por: Qiu, Dongxu, et al.
Publicado: (2020)

BTG2 suppresses renal cell carcinoma progression through N6-methyladenosine
por: Qi, Fuming, et al.
Publicado: (2022)

Comparison of clinical feasibility and oncological outcomes between video endoscopic and open inguinal lymphadenectomy for penile cancer: A systematic review and meta-analysis
por: Hu, Jiao, et al.
Publicado: (2019)

BCAT2 Shapes a Noninflamed Tumor Microenvironment and Induces Resistance to Anti‐PD‐1/PD‐L1 Immunotherapy by Negatively Regulating Proinflammatory Chemokines and Anticancer Immunity
por: Cai, Zhiyong, et al.
Publicado: (2023)

Predict Epitranscriptome Targets and Regulatory Functions of N(6)-Methyladenosine (m(6)A) Writers and Erasers
por: Song, Yiyou, et al.
Publicado: (2019)

Comprehensive Analysis of N6-Methyladenosine (m6A) Writers, Erasers, and Readers in Cervical Cancer
por: Condic, Mateja, et al.
Publicado: (2022)

Writers, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break Repair
por: Smeenk, Godelieve, et al.
Publicado: (2016)

Regulation of the oncogenic phenotype by the nuclear body protein ZC3H8
por: Schmidt, John A., et al.
Publicado: (2018)

Comprehensive immunohistochemical analysis of N6-methyladenosine (m6A) writers, erasers, and readers in endometrial cancer
por: Ralser, Damian J., et al.
Publicado: (2022)

Technology of Manufacturing of ZC Cylindrical Worm
por: Boral, Piotr, et al.
Publicado: (2022)

A novel signature to predict the neoadjuvant chemotherapy response of bladder carcinoma: Results from a territory multicenter real-world study
por: Li, Huihuang, et al.
Publicado: (2022)

Prediction of clinically significant prostate cancer using a novel (68)Ga-PSMA PET-CT and multiparametric MRI-based model
por: Cheng, Chunliang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_n7cdh5o5t1hp0i0aecok2cinlq