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Comparison of Drug Availability in the Inner Ear After Oral, Transtympanic, and Combined Administration

Although combination of oral and transtympanic drug therapy (CT) has been proved more effective and safer for idiopathic sudden sensorineural hearing loss (ISSNHL) by some clinical trials, there are few laboratory researches on the pharmacokinetics in the inner ear following CT on account of structu...

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Detalles Bibliográficos
Autores principales: Li, Yang, Kanzaki, Sho, Shibata, Shinsuke, Nakamura, Masaya, Ozaki, Masahiro, Okano, Hideyuki, Ogawa, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420880/
https://www.ncbi.nlm.nih.gov/pubmed/34497573
http://dx.doi.org/10.3389/fneur.2021.641593