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Comparison of Drug Availability in the Inner Ear After Oral, Transtympanic, and Combined Administration
Although combination of oral and transtympanic drug therapy (CT) has been proved more effective and safer for idiopathic sudden sensorineural hearing loss (ISSNHL) by some clinical trials, there are few laboratory researches on the pharmacokinetics in the inner ear following CT on account of structu...
Autores principales: | Li, Yang, Kanzaki, Sho, Shibata, Shinsuke, Nakamura, Masaya, Ozaki, Masahiro, Okano, Hideyuki, Ogawa, Kaoru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420880/ https://www.ncbi.nlm.nih.gov/pubmed/34497573 http://dx.doi.org/10.3389/fneur.2021.641593 |
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