Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif

The spike protein is the main protein component of the SARS-CoV-2 virion surface. The spike receptor-binding motif mediates recognition of the human angiotensin-converting enzyme 2 receptor, a critical step in infection, and is the preferential target for spike-neutralizing antibodies. Posttranslati...

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Detalles Bibliográficos
Autores principales: Lorenzo, Ramiro, Defelipe, Lucas A., Aliperti, Lucio, Niebling, Stephan, Custódio, Tânia F., Löw, Christian, Schwarz, Jennifer J., Remans, Kim, Craig, Patricio O., Otero, Lisandro H., Klinke, Sebastián, García-Alai, María, Sánchez, Ignacio E., Alonso, Leonardo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421091/
https://www.ncbi.nlm.nih.gov/pubmed/34499924
http://dx.doi.org/10.1016/j.jbc.2021.101175

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