Cargando…

The emergence and ongoing convergent evolution of the SARS-CoV-2 N501Y lineages

The independent emergence late in 2020 of the B.1.1.7, B.1.351, and P.1 lineages of SARS-CoV-2 prompted renewed concerns about the evolutionary capacity of this virus to overcome public health interventions and rising population immunity. Here, by examining patterns of synonymous and non-synonymous...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martin, Darren P., Weaver, Steven, Tegally, Houriiyah, San, James Emmanuel, Shank, Stephen D., Wilkinson, Eduan, Lucaci, Alexander G., Giandhari, Jennifer, Naidoo, Sureshnee, Pillay, Yeshnee, Singh, Lavanya, Lessells, Richard J., Gupta, Ravindra K., Wertheim, Joel O., Nekturenko, Anton, Murrell, Ben, Harkins, Gordon W., Lemey, Philippe, MacLean, Oscar A., Robertson, David L., de Oliveira, Tulio, Kosakovsky Pond, Sergei L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Published by Elsevier Inc. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421097/ https://www.ncbi.nlm.nih.gov/pubmed/34537136 http://dx.doi.org/10.1016/j.cell.2021.09.003

Ejemplares similares

The emergence and ongoing convergent evolution of the N501Y lineages coincides with a major global shift in the SARS-CoV-2 selective landscape
por: Martin, Darren P, et al.
Publicado: (2021)

Evaluation of miniaturized Illumina DNA preparation protocols for SARS-CoV-2 whole genome sequencing
por: Pillay, Sureshnee, et al.
Publicado: (2023)

Comparison of SARS-CoV-2 sequencing using the ONT GridION and the Illumina MiSeq
por: Tshiabuila, Derek, et al.
Publicado: (2022)

Molecular Epidemiology of SARS-CoV-2 during Five COVID-19 Waves and the Significance of Low-Frequency Lineages
por: Subramoney, Kathleen, et al.
Publicado: (2023)

Correction: Subramoney et al. Molecular Epidemiology of SARS-CoV-2 during Five COVID-19 Waves and the Significance of Low-Frequency Lineages. Viruses 2023, 15, 1194
por: Subramoney, Kathleen, et al.
Publicado: (2023)

High Resolution analysis of Transmission Dynamics of Sars-Cov-2 in Two Major Hospital Outbreaks in South Africa Leveraging Intrahost Diversity
por: James, San Emmanuel, et al.
Publicado: (2020)

Targeted Sanger sequencing to recover key mutations in SARS-CoV-2 variant genome assemblies produced by next-generation sequencing
por: Singh, Lavanya, et al.
Publicado: (2022)

SARS-CoV-2 spike protein diversity at an intra-host level, among SARS-CoV-2 infected individuals in South Africa, 2020 to 2022
por: Subramoney, Kathleen, et al.
Publicado: (2023)

Whole Genome Sequencing of SARS-CoV-2: Adapting Illumina Protocols for Quick and Accurate Outbreak Investigation during a Pandemic
por: Pillay, Sureshnee, et al.
Publicado: (2020)

Molecular Epidemiology and Diversity of SARS-CoV-2 in Ethiopia, 2020–2022
por: Sisay, Abay, et al.
Publicado: (2023)

Early transmission of SARS-CoV-2 in South Africa: An epidemiological and phylogenetic report
por: Giandhari, Jennifer, et al.
Publicado: (2020)

Early transmission of SARS-CoV-2 in South Africa: An epidemiological and phylogenetic report
por: Giandhari, Jennifer, et al.
Publicado: (2021)

Identification of SARS‐CoV‐2 Omicron variant using spike gene target failure and genotyping assays, Gauteng, South Africa, 2021
por: Subramoney, Kathleen, et al.
Publicado: (2022)

Transmission dynamics of SARS-CoV-2 within-host diversity in two major hospital outbreaks in South Africa
por: San, James E, et al.
Publicado: (2021)

Rapid Replacement of SARS-CoV-2 Variants by Delta and Subsequent Arrival of Omicron, Uganda, 2021
por: Bbosa, Nicholas, et al.
Publicado: (2022)

Genomic epidemiology of SARS-CoV-2 during the first four waves in Mozambique
por: Ismael, Nalia, et al.
Publicado: (2023)

Unlocking the efficiency of genomics laboratories with robotic liquid-handling
por: Tegally, Houriiyah, et al.
Publicado: (2020)

Selection analysis identifies unusual clustered mutational changes in Omicron lineage BA.1 that likely impact Spike function
por: Martin, Darren P, et al.
Publicado: (2022)

Selection Analysis Identifies Clusters of Unusual Mutational Changes in Omicron Lineage BA.1 That Likely Impact Spike Function
por: Martin, Darren P., et al.
Publicado: (2022)

Increasing HIV-1 Drug Resistance Between 2010 and 2012 in Adults Participating in Population-Based HIV Surveillance in Rural KwaZulu-Natal, South Africa
por: Manasa, Justen, et al.
Publicado: (2016)

Consequences of rpoB mutations missed by the GenoType MTBDRplus assay in a programmatic setting in South Africa
por: Mvelase, Nomonde R., et al.
Publicado: (2023)

Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection
por: Khan, Khadija, et al.
Publicado: (2022)

Author Correction: Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection
por: Khan, Khadija, et al.
Publicado: (2022)

Insights into SARS‐CoV‐2 in Angola during the COVID‐19 peak: Molecular epidemiology and genome surveillance
por: Francisco, Ngiambudulu M., et al.
Publicado: (2023)

Extra base hits: Widespread empirical support for instantaneous multiple-nucleotide changes
por: Lucaci, Alexander G., et al.
Publicado: (2021)

Multiple Early Introductions of SARS-CoV-2 to Cape Town, South Africa
por: Engelbrecht, Susan, et al.
Publicado: (2021)

Drug resistance in children at virological failure in a rural KwaZulu-Natal, South Africa, cohort
por: Pillay, Sureshnee, et al.
Publicado: (2014)

Modeling HIV-1 Drug Resistance as Episodic Directional Selection
por: Murrell, Ben, et al.
Publicado: (2012)

Detecting Individual Sites Subject to Episodic Diversifying Selection
por: Murrell, Ben, et al.
Publicado: (2012)

Implementation of an efficient SARS-CoV-2 specimen pooling strategy for high throughput diagnostic testing
por: Singh, Lavanya, et al.
Publicado: (2021)

Purifying Selection Can Obscure the Ancient Age of Viral Lineages
por: Wertheim, Joel O., et al.
Publicado: (2011)

Molecular Epidemiology and Trends in HIV-1 Transmitted Drug Resistance in Mozambique 1999–2018
por: Ismael, Nalia, et al.
Publicado: (2022)

Emergence of SARS-CoV-2 Omicron lineages BA.4 and BA.5 in South Africa
por: Tegally, Houriiyah, et al.
Publicado: (2022)

The evolution of BDNF is defined by strict purifying selection and prodomain spatial coevolution, but what does it mean for human brain disease?
por: Lucaci, Alexander G., et al.
Publicado: (2022)

On the Validity of Evolutionary Models with Site-Specific Parameters
por: Scheffler, Konrad, et al.
Publicado: (2014)

Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage
por: Scheepers, Cathrine, et al.
Publicado: (2022)

RASCL: RAPID ASSESSMENT OF SARS-COV-2 CLADES THROUGH MOLECULAR SEQUENCE ANALYSIS
por: Lucaci, Alexander G, et al.
Publicado: (2022)

Combining Phylogenetic and Network Approaches to Identify HIV-1 Transmission Links in San Mateo County, California
por: Dalai, Sudeb C., et al.
Publicado: (2018)

SARS-CoV-2 501Y.V2 (B.1.351) elicits cross-reactive neutralizing antibodies
por: Moyo-Gwete, Thandeka, et al.
Publicado: (2021)

Evolutionary Shortcuts via Multinucleotide Substitutions and Their Impact on Natural Selection Analyses
por: Lucaci, Alexander G, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_074o52bkn9aha0f87aqrgvvid7