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DNA G-quadruplex structures: more than simple roadblocks to transcription?

It has been >20 years since the formation of G-quadruplex (G4) secondary structures in gene promoters was first linked to the regulation of gene expression. Since then, the development of small molecules to selectively target G4s and their cellular application have contributed to an improved unde...

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Detalles Bibliográficos
Autores principales: Robinson, Jenna, Raguseo, Federica, Nuccio, Sabrina Pia, Liano, Denise, Di Antonio, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421137/
https://www.ncbi.nlm.nih.gov/pubmed/34255847
http://dx.doi.org/10.1093/nar/gkab609