Small-molecule compounds boost genome-editing efficiency of cytosine base editor

Cytosine base editor (CBE) enables targeted C-to-T conversions at single base-pair resolution and thus has potential therapeutic applications in humans. However, the low efficiency of the system limits practical use of this approach. We reported a high-throughput human cells-based reporter system th...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Tianyuan, Li, Qing, Zhou, Chenchen, Lv, Xiujuan, Liu, Hongyan, Tu, Tianxiang, Tang, Na, Cheng, Yanbo, Liu, Xiaoyu, Liu, Changbao, Zhao, Junzhao, Song, Zongming, Wang, Haoyi, Li, Jinsong, Gu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421147/
https://www.ncbi.nlm.nih.gov/pubmed/34329468
http://dx.doi.org/10.1093/nar/gkab645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421147/
https://www.ncbi.nlm.nih.gov/pubmed/34329468
http://dx.doi.org/10.1093/nar/gkab645

Ejemplares similares