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Small-molecule compounds boost genome-editing efficiency of cytosine base editor

Cytosine base editor (CBE) enables targeted C-to-T conversions at single base-pair resolution and thus has potential therapeutic applications in humans. However, the low efficiency of the system limits practical use of this approach. We reported a high-throughput human cells-based reporter system th...

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Detalles Bibliográficos
Autores principales:	Zhao, Tianyuan, Li, Qing, Zhou, Chenchen, Lv, Xiujuan, Liu, Hongyan, Tu, Tianxiang, Tang, Na, Cheng, Yanbo, Liu, Xiaoyu, Liu, Changbao, Zhao, Junzhao, Song, Zongming, Wang, Haoyi, Li, Jinsong, Gu, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Synthetic Biology and Bioengineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421147/ https://www.ncbi.nlm.nih.gov/pubmed/34329468 http://dx.doi.org/10.1093/nar/gkab645

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