Global detection of DNA repair outcomes induced by CRISPR–Cas9

CRISPR–Cas9 generates double-stranded DNA breaks (DSBs) to activate cellular DNA repair pathways for genome editing. The repair of DSBs leads to small insertions or deletions (indels) and other complex byproducts, including large deletions and chromosomal translocations. Indels are well understood t...

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Detalles Bibliográficos
Autores principales: Liu, Mengzhu, Zhang, Weiwei, Xin, Changchang, Yin, Jianhang, Shang, Yafang, Ai, Chen, Li, Jiaxin, Meng, Fei-Long, Hu, Jiazhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421148/
https://www.ncbi.nlm.nih.gov/pubmed/34365511
http://dx.doi.org/10.1093/nar/gkab686

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