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Endogenous piRNA-guided slicing triggers responder and trailer piRNA production from viral RNA in Aedes aegypti mosquitoes

In the germline of animals, PIWI interacting (pi)RNAs protect the genome against the detrimental effects of transposon mobilization. In Drosophila, piRNA-mediated cleavage of transposon RNA triggers the production of responder piRNAs via ping-pong amplification. Responder piRNA 3′ end formation by t...

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Detalles Bibliográficos
Autores principales: Joosten, Joep, Overheul, Gijs J, Van Rij, Ronald P, Miesen, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421150/
https://www.ncbi.nlm.nih.gov/pubmed/34331446
http://dx.doi.org/10.1093/nar/gkab640