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Grand scale genome manipulation via chromosome swapping in Escherichia coli programmed by three one megabase chromosomes

In bacterial synthetic biology, whole genome transplantation has been achieved only in mycoplasmas that contain a small genome and are competent for foreign genome uptake. In this study, we developed Escherichia coli strains programmed by three 1-megabase (Mb) chromosomes by splitting the 3-Mb chrom...

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Detalles Bibliográficos
Autores principales: Yoneji, Tatsuya, Fujita, Hironobu, Mukai, Takahito, Su’etsugu, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421210/
https://www.ncbi.nlm.nih.gov/pubmed/33907814
http://dx.doi.org/10.1093/nar/gkab298