Testing mechanisms of DNA sliding by architectural DNA-binding proteins: dynamics of single wild-type and mutant protein molecules in vitro and in vivo

Architectural DNA-binding proteins (ADBPs) are abundant constituents of eukaryotic or bacterial chromosomes that bind DNA promiscuously and function in diverse DNA reactions. They generate large conformational changes in DNA upon binding yet can slide along DNA when searching for functional binding...

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Detalles Bibliográficos
Autores principales: Kamagata, Kiyoto, Itoh, Yuji, Tan, Cheng, Mano, Eriko, Wu, Yining, Mandali, Sridhar, Takada, Shoji, Johnson, Reid C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421229/
https://www.ncbi.nlm.nih.gov/pubmed/34352099
http://dx.doi.org/10.1093/nar/gkab658

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