Systematic identification of novel cancer genes through analysis of deep shRNA perturbation screens

Systematic perturbation screens provide comprehensive resources for the elucidation of cancer driver genes. The perturbation of many genes in relatively few cell lines in such functional screens necessitates the development of specialized computational tools with sufficient statistical power. Here w...

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Detalles Bibliográficos
Autores principales: Montazeri, Hesam, Coto-Llerena, Mairene, Bianco, Gaia, Zangene, Ehsan, Taha-Mehlitz, Stephanie, Paradiso, Viola, Srivatsa, Sumana, de Weck, Antoine, Roma, Guglielmo, Lanzafame, Manuela, Bolli, Martin, Beerenwinkel, Niko, von Flüe, Markus, Terracciano, Luigi M, Piscuoglio, Salvatore, Ng, Charlotte K Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421231/
https://www.ncbi.nlm.nih.gov/pubmed/34313788
http://dx.doi.org/10.1093/nar/gkab627

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