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Improvement of Pulmonary Function in Heart Failure Patients with Restrictive Patterns Undergoing Transcatheter Aortic Valve Replacement

BACKGROUND: This study aimed to investigate the improvement of pulmonary function in heart failure patients with restrictive patterns undergoing transcatheter aortic valve replacement (TAVR). METHODS: A total of 80 patients with heart failure and restrictive patterns undergoing TAVR due to severe ao...

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Autores principales: Karacop, Handan Basel, Karacop, Erdem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421250/
https://www.ncbi.nlm.nih.gov/pubmed/34511998
http://dx.doi.org/10.2147/IJGM.S309175
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author Karacop, Handan Basel
Karacop, Erdem
author_facet Karacop, Handan Basel
Karacop, Erdem
author_sort Karacop, Handan Basel
collection PubMed
description BACKGROUND: This study aimed to investigate the improvement of pulmonary function in heart failure patients with restrictive patterns undergoing transcatheter aortic valve replacement (TAVR). METHODS: A total of 80 patients with heart failure and restrictive patterns undergoing TAVR due to severe aortic stenosis were included in this study. Spirometry and gas diffusion were assessed before and 4–6 months after TAVR. Pre- and post-TAVR measures were compared using paired t-tests. RESULTS: Spirometry demonstrated increased absolute and percentage predicted total lung capacity (TLC), forced vital capacity (FVC), residual volume (RV), forced expiratory volume in the first second (FEV1), and forced vital capacity (FVC). FEV1/FVC decreased due to a pronounced increase in FVC. Additionally, the diffusing capacity for carbon monoxide (DLCO) increased significantly. CONCLUSION: Pulmonary function improves in heart failure patients with restrictive patterns undergoing TAVR.
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spelling pubmed-84212502021-09-09 Improvement of Pulmonary Function in Heart Failure Patients with Restrictive Patterns Undergoing Transcatheter Aortic Valve Replacement Karacop, Handan Basel Karacop, Erdem Int J Gen Med Original Research BACKGROUND: This study aimed to investigate the improvement of pulmonary function in heart failure patients with restrictive patterns undergoing transcatheter aortic valve replacement (TAVR). METHODS: A total of 80 patients with heart failure and restrictive patterns undergoing TAVR due to severe aortic stenosis were included in this study. Spirometry and gas diffusion were assessed before and 4–6 months after TAVR. Pre- and post-TAVR measures were compared using paired t-tests. RESULTS: Spirometry demonstrated increased absolute and percentage predicted total lung capacity (TLC), forced vital capacity (FVC), residual volume (RV), forced expiratory volume in the first second (FEV1), and forced vital capacity (FVC). FEV1/FVC decreased due to a pronounced increase in FVC. Additionally, the diffusing capacity for carbon monoxide (DLCO) increased significantly. CONCLUSION: Pulmonary function improves in heart failure patients with restrictive patterns undergoing TAVR. Dove 2021-09-02 /pmc/articles/PMC8421250/ /pubmed/34511998 http://dx.doi.org/10.2147/IJGM.S309175 Text en © 2021 Karacop and Karacop. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Karacop, Handan Basel
Karacop, Erdem
Improvement of Pulmonary Function in Heart Failure Patients with Restrictive Patterns Undergoing Transcatheter Aortic Valve Replacement
title Improvement of Pulmonary Function in Heart Failure Patients with Restrictive Patterns Undergoing Transcatheter Aortic Valve Replacement
title_full Improvement of Pulmonary Function in Heart Failure Patients with Restrictive Patterns Undergoing Transcatheter Aortic Valve Replacement
title_fullStr Improvement of Pulmonary Function in Heart Failure Patients with Restrictive Patterns Undergoing Transcatheter Aortic Valve Replacement
title_full_unstemmed Improvement of Pulmonary Function in Heart Failure Patients with Restrictive Patterns Undergoing Transcatheter Aortic Valve Replacement
title_short Improvement of Pulmonary Function in Heart Failure Patients with Restrictive Patterns Undergoing Transcatheter Aortic Valve Replacement
title_sort improvement of pulmonary function in heart failure patients with restrictive patterns undergoing transcatheter aortic valve replacement
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421250/
https://www.ncbi.nlm.nih.gov/pubmed/34511998
http://dx.doi.org/10.2147/IJGM.S309175
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