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Arkadia-SKI/SnoN signaling differentially regulates TGF-β–induced iTreg and Th17 cell differentiation

TGF-β signaling is fundamental for both Th17 and regulatory T (Treg) cell differentiation. However, these cells differ in requirements for downstream signaling components, such as SMAD effectors. To further characterize mechanisms that distinguish TGF-β signaling requirements for Th17 and Treg cell...

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Detalles Bibliográficos
Autores principales: Xu, Hao, Wu, Lin, Nguyen, Henry H., Mesa, Kailin R., Raghavan, Varsha, Episkopou, Vasso, Littman, Dan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421263/
https://www.ncbi.nlm.nih.gov/pubmed/34473197
http://dx.doi.org/10.1084/jem.20210777