A TLR7 antagonist restricts interferon-dependent and -independent immunopathology in a mouse model of severe influenza

Cytokine-mediated immune-cell recruitment and inflammation contribute to protection in respiratory virus infection. However, uncontrolled inflammation and the “cytokine storm” are hallmarks of immunopathology in severe infection. Cytokine storm is a broad term for a phenomenon with diverse character...

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Detalles Bibliográficos
Autores principales: Rappe, Julie C.F., Finsterbusch, Katja, Crotta, Stefania, Mack, Matthias, Priestnall, Simon L., Wack, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421264/
https://www.ncbi.nlm.nih.gov/pubmed/34473195
http://dx.doi.org/10.1084/jem.20201631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421264/
https://www.ncbi.nlm.nih.gov/pubmed/34473195
http://dx.doi.org/10.1084/jem.20201631

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