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GOLPH3 and GOLPH3L are broad-spectrum COPI adaptors for sorting into intra-Golgi transport vesicles

The fidelity of Golgi glycosylation is, in part, ensured by compartmentalization of enzymes within the stack. The COPI adaptor GOLPH3 has been shown to interact with the cytoplasmic tails of a subset of Golgi enzymes and direct their retention. However, other mechanisms of retention, and other roles...

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Detalles Bibliográficos
Autores principales: Welch, Lawrence G., Peak-Chew, Sew-Yeu, Begum, Farida, Stevens, Tim J., Munro, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421267/
https://www.ncbi.nlm.nih.gov/pubmed/34473204
http://dx.doi.org/10.1083/jcb.202106115

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