Cargando…
HSPA9/Mortalin mediates axo-protection and modulates mitochondrial dynamics in neurons
Mortalin is a mitochondrial chaperone protein involved in quality control of proteins imported into the mitochondrial matrix, which was recently described as a sensor of neuronal stress. Mortalin is down-regulated in neurons of patients with neurodegenerative diseases and levels of Mortalin expressi...
Autores principales: | Ferré, Cécile A., Thouard, Anne, Bétourné, Alexandre, Le Dorze, Anne-Louise, Belenguer, Pascale, Miquel, Marie-Christine, Peyrin, Jean-Michel, Gonzalez-Dunia, Daniel, Szelechowski, Marion |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421332/ https://www.ncbi.nlm.nih.gov/pubmed/34489498 http://dx.doi.org/10.1038/s41598-021-97162-1 |
Ejemplares similares
-
Mortalin/Hspa9 involvement and therapeutic perspective in Parkinson’s disease
por: Texier, Baptiste, et al.
Publicado: (2022) -
Mortalin/HSPA9 targeting selectively induces KRAS tumor cell death by perturbing mitochondrial membrane permeability
por: Wu, Pui-Kei, et al.
Publicado: (2020) -
Mortalin (GRP75/HSPA9) Promotes Survival and Proliferation of Thyroid Carcinoma Cells
por: Starenki, Dmytro, et al.
Publicado: (2019) -
Mortalin (GRP75/HSPA9) upregulation promotes survival and proliferation of medullary thyroid carcinoma cells
por: Starenki, Dmytro, et al.
Publicado: (2014) -
Enhanced primary ciliogenesis via mitochondrial oxidative stress activates AKT to prevent neurotoxicity in HSPA9/mortalin-depleted SH-SY5Y cells
por: Bae, Ji-Eun, et al.
Publicado: (2023)