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Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis

Esophageal squamous-cell carcinoma (ESCC), one of the most prevalent and lethal malignant disease, has a complex but unknown tumor ecosystem. Here, we investigate the composition of ESCC tumors based on 208,659 single-cell transcriptomes derived from 60 individuals. We identify 8 common expression p...

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Detalles Bibliográficos
Autores principales: Zhang, Xiannian, Peng, Linna, Luo, Yingying, Zhang, Shaosen, Pu, Yang, Chen, Yamei, Guo, Wenjia, Yao, Jiacheng, Shao, Mingming, Fan, Wenyi, Cui, Qionghua, Xi, Yiyi, Sun, Yanxia, Niu, Xiangjie, Zhao, Xuan, Chen, Liping, Wang, Yuqian, Liu, Yachen, Yang, Xinyu, Wang, Chengcheng, Zhong, Ce, Tan, Wen, Wang, Jianbin, Wu, Chen, Lin, Dongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421382/
https://www.ncbi.nlm.nih.gov/pubmed/34489433
http://dx.doi.org/10.1038/s41467-021-25539-x