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Binding of regulatory proteins to nucleosomes is modulated by dynamic histone tails

Little is known about the roles of histone tails in modulating nucleosomal DNA accessibility and its recognition by other macromolecules. Here we generate extensive atomic level conformational ensembles of histone tails in the context of the full nucleosome, totaling 65 microseconds of molecular dyn...

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Detalles Bibliográficos
Autores principales:	Peng, Yunhui, Li, Shuxiang, Onufriev, Alexey, Landsman, David, Panchenko, Anna R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421395/ https://www.ncbi.nlm.nih.gov/pubmed/34489435 http://dx.doi.org/10.1038/s41467-021-25568-6

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