Cyclic pulsation stress promotes bone formation of tissue engineered laminae through the F-actin/YAP-1/β-Catenin signaling axis

Mechanical loads are fundamental regulators of bone formation and remodeling. However, the molecular regulation of mechanotransduction during vertebral laminae regeneration remains poorly understood. Here, we found that cerebrospinal fluid pulsation (CSFP) stress—cyclic pulsation stress—could promot...

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Detalles Bibliográficos
Autores principales: Li, Linli, Li, Hailong, He, Yiqun, Tang, Han, Dong, Jian, Chen, Xujun, Lyu, Feizhou, Dong, Youhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421434/
https://www.ncbi.nlm.nih.gov/pubmed/34489466
http://dx.doi.org/10.1038/s41536-021-00164-w

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