Coordination of EZH2 and SOX2 specifies human neural fate decision

Polycomb repressive complexes (PRCs) are essential in mouse gastrulation and specify neural ectoderm in human embryonic stem cells (hESCs), but the underlying molecular basis remains unclear. Here in this study, by employing an array of different approaches, such as gene knock-out, RNA-seq, ChIP-seq...

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Detalles Bibliográficos
Autores principales: Zhao, Yuan, Wang, Tianyu, Zhang, Yanqi, Shi, Liang, Zhang, Cong, Zhang, Jingyuan, Yao, Jiao, Chen, Qianyu, Zhong, Xiaofen, Wei, Yanxing, Shan, Yongli, Pan, Guangjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421500/
https://www.ncbi.nlm.nih.gov/pubmed/34487238
http://dx.doi.org/10.1186/s13619-021-00092-6

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