Cargando…
Leptin sensitizing effect of 1,3-butanediol and its potential mechanism
Leptin is an adipocyte-derived hormone that regulates appetite and energy expenditure via the hypothalamus. Since the majority of obese subjects are leptin resistant, leptin sensitizers, rather than leptin itself, are expected to be anti-obesity drugs. Endoplasmic reticulum (ER) stress in the hypoth...
Autores principales: | Isoda, Masayo, Ebihara, Ken, Sawayama, Nagisa, Murakami, Akiko, Ebihara, Chihiro, Shibuya, Koji, Takei, Akihito, Takei, Shoko, Wakabayashi, Tetsuji, Yamamuro, Daisuke, Takahashi, Manabu, Nagashima, Shuichi, Ishibashi, Shun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421515/ https://www.ncbi.nlm.nih.gov/pubmed/34489483 http://dx.doi.org/10.1038/s41598-021-96460-y |
Ejemplares similares
-
AAA-ATPase valosin-containing protein binds the transcription factor SREBP1 and promotes its proteolytic activation by rhomboid protease RHBDL4
por: Shibuya, Koji, et al.
Publicado: (2022) -
SUN-096 Hypothalamic ATP Has a Crucial Role in the Pathogenesis of Leptin Resistance: A Potential Mechanism for the Amelioration of Leptin Resistance by Celastrol and Withaferin A
por: Ebihara, Chihiro, et al.
Publicado: (2019) -
Loss of myeloid lipoprotein lipase exacerbates adipose tissue fibrosis with collagen VI deposition and hyperlipidemia in leptin-deficient obese mice
por: Takahashi, Manabu, et al.
Publicado: (2022) -
Loss of ACAT1 Attenuates Atherosclerosis Aggravated by Loss of NCEH1 in Bone Marrow-Derived Cells
por: Yamazaki, Hisataka, et al.
Publicado: (2019) -
Peripheral circadian rhythms in the liver and white adipose tissue of mice are attenuated by constant light and restored by time-restricted feeding
por: Yamamuro, Daisuke, et al.
Publicado: (2020)