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Elevated Fibronectin Levels in Profibrotic CD14(+) Monocytes and CD14(+) Macrophages in Systemic Sclerosis

BACKGROUND: Systemic sclerosis (SSc) is an autoimmune disease characterized by overproduction of extracellular matrix (ECM) and multiorgan fibrosis. Animal studies pointed to bone marrow-derived cells as a potential source of pathological ECM-producing cells in immunofibrotic disorders. So far, invo...

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Detalles Bibliográficos
Autores principales: Rudnik, Michał, Hukara, Amela, Kocherova, Ievgeniia, Jordan, Suzana, Schniering, Janine, Milleret, Vincent, Ehrbar, Martin, Klingel, Karin, Feghali-Bostwick, Carol, Distler, Oliver, Błyszczuk, Przemysław, Kania, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421541/
https://www.ncbi.nlm.nih.gov/pubmed/34504485
http://dx.doi.org/10.3389/fimmu.2021.642891