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Investigation of MDMA Inhibitory Effect on CytochromeP450 3A4 in Isolated Perfused Rat Liver Model Using Tramadol

Purpose: MDMA (methylenedioxymethamphetamine) is a synthetic compound, which is a structurally derivative of amphetamine. Also, it acts like an amphetamine, structurally, and functionally. MDMA uses mechanism-based inhibition, to inhibit isoenzyme CYP2D6. It can also inhibit other isoenzymes contrib...

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Detalles Bibliográficos
Autores principales: Sheikholeslami, Behjat, Tootoonchi, Zahra, Lavasani, Hoda, Hosseinzadeh Ardakani, Yalda, Rouini, Mohammadreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421619/
https://www.ncbi.nlm.nih.gov/pubmed/34513628
http://dx.doi.org/10.34172/apb.2021.061