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Importance of Nano Medicine and New Drug Therapies for Cancer
Cancer is one of the deadly diseases leading to approximately 7.6 million deaths worldwide, with the mortality rate of 13%, and the number of deaths is expected to increase to 13.1 million within the next 10 years. In controlled drug delivery systems (DDS), the drug is transported to the desired loc...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tabriz University of Medical Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421622/ https://www.ncbi.nlm.nih.gov/pubmed/34513619 http://dx.doi.org/10.34172/apb.2021.052 |
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author | Abdolmaleki, Arash Asadi, Asadollah Gurushankar, Krishnamoorthy Karimi Shayan, Tahereh Abedi Sarvestani, Fatemeh |
author_facet | Abdolmaleki, Arash Asadi, Asadollah Gurushankar, Krishnamoorthy Karimi Shayan, Tahereh Abedi Sarvestani, Fatemeh |
author_sort | Abdolmaleki, Arash |
collection | PubMed |
description | Cancer is one of the deadly diseases leading to approximately 7.6 million deaths worldwide, with the mortality rate of 13%, and the number of deaths is expected to increase to 13.1 million within the next 10 years. In controlled drug delivery systems (DDS), the drug is transported to the desired location. Thus, the influence of drugs on vital tissues and undesirable side effects can be minimised. Additionally, DDS protects the drug from rapid degradation or clearance and enhances drug concentration in target tissues, and therefore, minimise the required dose of drug. This modern form of therapy is particularly important when there is a discrepancy between the dose and concentration of a drug. Cell-specific targeting can be achieved by attaching drugs to individually designed carriers. Recent developments in nanotechnology have shown that nanoparticles (particles with diameter < 100 nm in at least one dimension) have great potential as drug carriers. Because of their small size, these nanostructures exhibit unique physicochemical and biological properties that make them a favourable material for biomedical applications. Therefore, in this review, we aimed to describe the importance and types of nanomedicines and efficient ways in which new drug delivery systems for the treatment of cancer can be developed. |
format | Online Article Text |
id | pubmed-8421622 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Tabriz University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-84216222021-09-09 Importance of Nano Medicine and New Drug Therapies for Cancer Abdolmaleki, Arash Asadi, Asadollah Gurushankar, Krishnamoorthy Karimi Shayan, Tahereh Abedi Sarvestani, Fatemeh Adv Pharm Bull Mini Review Cancer is one of the deadly diseases leading to approximately 7.6 million deaths worldwide, with the mortality rate of 13%, and the number of deaths is expected to increase to 13.1 million within the next 10 years. In controlled drug delivery systems (DDS), the drug is transported to the desired location. Thus, the influence of drugs on vital tissues and undesirable side effects can be minimised. Additionally, DDS protects the drug from rapid degradation or clearance and enhances drug concentration in target tissues, and therefore, minimise the required dose of drug. This modern form of therapy is particularly important when there is a discrepancy between the dose and concentration of a drug. Cell-specific targeting can be achieved by attaching drugs to individually designed carriers. Recent developments in nanotechnology have shown that nanoparticles (particles with diameter < 100 nm in at least one dimension) have great potential as drug carriers. Because of their small size, these nanostructures exhibit unique physicochemical and biological properties that make them a favourable material for biomedical applications. Therefore, in this review, we aimed to describe the importance and types of nanomedicines and efficient ways in which new drug delivery systems for the treatment of cancer can be developed. Tabriz University of Medical Sciences 2021-06 2020-10-19 /pmc/articles/PMC8421622/ /pubmed/34513619 http://dx.doi.org/10.34172/apb.2021.052 Text en ©2021 The Authors. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, as long as the original authors and source are cited. No permission is required from the authors or the publishers. |
spellingShingle | Mini Review Abdolmaleki, Arash Asadi, Asadollah Gurushankar, Krishnamoorthy Karimi Shayan, Tahereh Abedi Sarvestani, Fatemeh Importance of Nano Medicine and New Drug Therapies for Cancer |
title | Importance of Nano Medicine and New Drug Therapies for Cancer |
title_full | Importance of Nano Medicine and New Drug Therapies for Cancer |
title_fullStr | Importance of Nano Medicine and New Drug Therapies for Cancer |
title_full_unstemmed | Importance of Nano Medicine and New Drug Therapies for Cancer |
title_short | Importance of Nano Medicine and New Drug Therapies for Cancer |
title_sort | importance of nano medicine and new drug therapies for cancer |
topic | Mini Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421622/ https://www.ncbi.nlm.nih.gov/pubmed/34513619 http://dx.doi.org/10.34172/apb.2021.052 |
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