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Substrate Stiffness Modulates the Growth, Phenotype, and Chemoresistance of Ovarian Cancer Cells

Mechanical factors in the tumor microenvironment play an important role in response to a variety of cellular activities in cancer cells. Here, we utilized polyacrylamide hydrogels with varying physical parameters simulating tumor and metastatic target tissues to investigate the effect of substrate s...

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Detalles Bibliográficos
Autores principales:	Fan, Yali, Sun, Quanmei, Li, Xia, Feng, Jiantao, Ao, Zhuo, Li, Xiang, Wang, Jiandong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421636/ https://www.ncbi.nlm.nih.gov/pubmed/34504843 http://dx.doi.org/10.3389/fcell.2021.718834

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