Alteration of TGFB1, GDF9, and BMPR2 gene expression in preantral follicles of an estradiol valerate-induced polycystic ovary mouse model can lead to anovulation, polycystic morphology, obesity, and absence of hyperandrogenism

OBJECTIVE: In humans, polycystic ovary syndrome (PCOS) is an androgen-dependent ovarian disorder. Aberrant gene expression in folliculogenesis can arrest the transition of preantral to antral follicles, leading to PCOS. We explored the possible role of altered gene expression in preantral follicles...

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Detalles Bibliográficos
Autores principales: Asghari, Reza, Shokri-Asl, Vahid, Rezaei, Hanieh, Tavallaie, Mahmood, Khafaei, Mostafa, Abdolmaleki, Amir, Majdi Seghinsara, Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Reproductive Medicine 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421654/
https://www.ncbi.nlm.nih.gov/pubmed/34370943
http://dx.doi.org/10.5653/cerm.2020.04112

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