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Cystatin-B Negatively Regulates the Malignant Characteristics of Oral Squamous Cell Carcinoma Possibly Via the Epithelium Proliferation/Differentiation Program

Disturbance in the proteolytic process is one of the malignant signs of tumors. Proteolysis is highly orchestrated by cysteine cathepsin and its inhibitors. Cystatin-B (CSTB) is a general cysteine cathepsin inhibitor that prevents cysteine cathepsin from leaking from lysosomes and causing inappropri...

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Detalles Bibliográficos
Autores principales: Xu, Tian-Tian, Zeng, Xiao-Wen, Wang, Xin-Hong, Yang, Lu-Xi, Luo, Gang, Yu, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421684/
https://www.ncbi.nlm.nih.gov/pubmed/34504787
http://dx.doi.org/10.3389/fonc.2021.707066