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RanBP3 Regulates Proliferation, Apoptosis and Chemosensitivity of Chronic Myeloid Leukemia Cells via Mediating SMAD2/3 and ERK1/2 Nuclear Transport

Abnormal subcellular localization of proteins is an important cause of tumorigenesis and drug resistance. Chromosome region maintenance 1 (CRM1), the nuclear export regulator of most proteins, has been confirmed to be over-expressed in various malignancies and is regarded as an efficient target. But...

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Detalles Bibliográficos
Autores principales:	Li, Qian, Huang, Zhenglan, Peng, Yuhang, Wang, Xin, Jiang, Guoyun, Wang, Teng, Mou, Ke, Feng, Wenli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421687/ https://www.ncbi.nlm.nih.gov/pubmed/34504783 http://dx.doi.org/10.3389/fonc.2021.698410

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