When Leptin Is Not There: A Review of What Nonsyndromic Monogenic Obesity Cases Tell Us and the Benefits of Exogenous Leptin

Obesity is a pandemic condition of complex etiology, resulting from the increasing exposition to obesogenic environmental factors combined with genetic susceptibility. In the past two decades, advances in genetic research identified variants of the leptin-melanocortin pathway coding for genes, which...

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Detalles Bibliográficos
Autores principales: Salum, Kaio Cezar Rodrigues, Rolando, Jônatas de Mendonça, Zembrzuski, Verônica Marques, Carneiro, João Regis Ivar, Mello, Cicero Brasileiro, Maya-Monteiro, Clarissa Menezes, Bozza, Patrícia Torres, Kohlrausch, Fabiana Barzotto, da Fonseca, Ana Carolina Proença
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421737/
https://www.ncbi.nlm.nih.gov/pubmed/34504472
http://dx.doi.org/10.3389/fendo.2021.722441

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