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Transforming Growth Factor-β1 Promotes M1 Alveolar Macrophage Polarization in Acute Lung Injury by Up-Regulating DNMT1 to Mediate the microRNA-124/PELI1/IRF5 Axis

OBJECTIVE: Macrophages function as key orchestrators in the pathogenesis of acute lung injury (ALI). The current study sets out to investigate the molecular mechanism of transforming growth factor-β (TGFβ1) in the regulation of M1 alveolar macrophage polarization in ALI by modulating DNA methyltrans...

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Detalles Bibliográficos
Autores principales:	Wang, Yongqi, Wang, Xiaoqing, Zhang, Hong, Han, Biao, Ye, Yuanmei, Zhang, Mengjie, Wang, Yingbin, Xue, Jianjun, Wang, Chun’ai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421846/ https://www.ncbi.nlm.nih.gov/pubmed/34504806 http://dx.doi.org/10.3389/fcimb.2021.693981

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