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Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis

Inhibition of mTOR is the standard of care for lymphangioleiomyomatosis (LAM). However, this therapy has variable tolerability and some patients show progressive decline of lung function despite treatment. LAM diagnosis and monitoring can also be challenging due to the heterogeneity of symptoms and...

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Detalles Bibliográficos
Autores principales: Herranz, Carmen, Mateo, Francesca, Baiges, Alexandra, Ruiz de Garibay, Gorka, Junza, Alexandra, Johnson, Simon R, Miller, Suzanne, García, Nadia, Capellades, Jordi, Gómez, Antonio, Vidal, August, Palomero, Luis, Espín, Roderic, Extremera, Ana I, Blommaert, Eline, Revilla‐López, Eva, Saez, Berta, Gómez‐Ollés, Susana, Ancochea, Julio, Valenzuela, Claudia, Alonso, Tamara, Ussetti, Piedad, Laporta, Rosalía, Xaubet, Antoni, Rodríguez‐Portal, José A, Montes‐Worboys, Ana, Machahua, Carlos, Bordas, Jaume, Menendez, Javier A, Cruzado, Josep M, Guiteras, Roser, Bontoux, Christophe, La Motta, Concettina, Noguera‐Castells, Aleix, Mancino, Mario, Lastra, Enrique, Rigo‐Bonnin, Raúl, Perales, Jose C, Viñals, Francesc, Lahiguera, Alvaro, Zhang, Xiaohu, Cuadras, Daniel, van Moorsel, Coline H M, van der Vis, Joanne J, Quanjel, Marian J R, Filippakis, Harilaos, Hakem, Razq, Gorrini, Chiara, Ferrer, Marc, Ugun‐Klusek, Aslihan, Billett, Ellen, Radzikowska, Elżbieta, Casanova, Álvaro, Molina‐Molina, María, Roman, Antonio, Yanes, Oscar, Pujana, Miquel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422079/
https://www.ncbi.nlm.nih.gov/pubmed/34378323
http://dx.doi.org/10.15252/emmm.202113929