Cargando…

Identification and validation of a metabolism-related model and associated with tumor-infiltrating lymphocytes in p53 mutant lung adenocarcinoma patients

BACKGROUND: The immunosuppressive tumor microenvironment produced by cancer cells is a key mechanisms of cancer immune escape. In this study, we investigated the relationship between the metabolic patterns and tumor immune environment in the TME of lung adenocarcinoma (LUAD) with the p53 mutation. M...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Chang, Sun, Liang, Zhou, Baosen, Wang, Aiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422113/ https://www.ncbi.nlm.nih.gov/pubmed/34532449 http://dx.doi.org/10.21037/atm-21-3234

Ejemplares similares

Cytological features of lung adenocarcinoma with massive lymphocyte infiltration
por: Álvarez-Rodríguez, F, et al.
Publicado: (2012)

Relationship between consolidation tumor ratio and tumor‐infiltrating lymphocytes in small‐sized lung adenocarcinoma
por: Ono, Yuki, et al.
Publicado: (2022)

Computerized tumor-infiltrating lymphocytes density score predicts survival of patients with resectable lung adenocarcinoma
por: Pan, Xipeng, et al.
Publicado: (2022)

Exploration of genes and tumor infiltrating lymphocytes in female lung adenocarcinoma microenvironment that predicted prognosis
por: Wang, Lijun, et al.
Publicado: (2021)

Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosis
por: Chou, Cheng-Wei, et al.
Publicado: (2019)

Digital Image Analysis for Estimating Stromal CD8+ Tumor-Infiltrating Lymphocytes in Lung Adenocarcinoma
por: Jhun, Iny, et al.
Publicado: (2021)

Association between p53 Expression and Amount of Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer
por: Lee, Miseon, et al.
Publicado: (2019)

Development and Validation of a Prognostic Autophagy-Related Gene Pair Index Related to Tumor-Infiltrating Lymphocytes in Early-Stage Lung Adenocarcinoma
por: Wang, Zi-Hao, et al.
Publicado: (2021)

Identification and validation of an immune cell infiltrating score predicting survival in patients with lung adenocarcinoma
por: Yang, Xiaodong, et al.
Publicado: (2019)

RASAL3 predicts overall survival and CD8+ T lymphocyte infiltration in lung adenocarcinoma
por: Liang, Mei, et al.
Publicado: (2022)

A Novel P53-Related Activity in a Colon Adenocarcinoma Cell Line With Mutant P53
por: Gartel, Andrei L., et al.
Publicado: (2001)

Tumor-infiltration of T-lymphocytes is inversely correlated with clinicopathologic factors in endometrial adenocarcinoma
por: Jung, In Kook, et al.
Publicado: (2014)

Regulation of arachidonic acid in esophageal adenocarcinoma cells and tumor-infiltrating lymphocytes
por: SONG, WEI, et al.
Publicado: (2013)

The prognostic significance of tumor-infiltrating lymphocytes assessment with hematoxylin and eosin sections in resected primary lung adenocarcinoma
por: Kim, Ahrong, et al.
Publicado: (2019)

Clinical outcome and expression of mutant P53, P16, and Smad4 in lung adenocarcinoma: a prospective study
por: Bian, Chunan, et al.
Publicado: (2015)

Tumor-Associated Mutant p53 Drives the Warburg Effect
por: Zhang, Cen, et al.
Publicado: (2013)

Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1α
por: Basu, Subhasree, et al.
Publicado: (2018)

Mutant p53(R270H) drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma
por: Schofield, Heather K., et al.
Publicado: (2018)

Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma
por: Tian, Wen, et al.
Publicado: (2021)

The Identification of Two RNA Modification Patterns and Tumor Microenvironment Infiltration Characterization of Lung Adenocarcinoma
por: He, Wan, et al.
Publicado: (2022)

Coexisting EGFR and TP53 Mutations in Lung Adenocarcinoma Patients Are Associated With COMP and ITGB8 Upregulation and Poor Prognosis
por: Zheng, Chang, et al.
Publicado: (2020)

Identification of Small Molecules that Modulate Mutant p53 Condensation
por: Lemos, Clara, et al.
Publicado: (2020)

Epitope identification for p53R273C mutant
por: Zhang, Jian, et al.
Publicado: (2022)

Increased Plasma Cells and Decreased B-cells in Tumor Infiltrating Lymphocytes are Associated with Worse Survival in Lung Adenocarcinomas
por: Lee, Hee Eun, et al.
Publicado: (2020)

AURKA and FAM83A are prognostic biomarkers and correlated with Tumor-infiltrating Lymphocytes in smoking related Lung Adenocarcinoma
por: Zhang, Mengyu, et al.
Publicado: (2021)

Tumor-infiltrating platelets promote the growth of lung adenocarcinoma
por: Li, Xiaohui, et al.
Publicado: (2023)

A special prognostic indicator: tumor mutation burden combined with immune infiltrates in lung adenocarcinoma with TP53 mutation
por: Fu, Jing, et al.
Publicado: (2021)

Correction for: Integrative analysis of exosomal microRNA-149-5p in lung adenocarcinoma
por: Tian, Wen, et al.
Publicado: (2022)

Suppression of gain-of-function mutant p53 with metabolic inhibitors reduces tumor growth in vivo
por: Jung, Chae Lim, et al.
Publicado: (2016)

Mutant p53 regulates Survivin to foster lung metastasis
por: Tang, Qiaosi, et al.
Publicado: (2021)

A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis
por: Yue, Xuetian, et al.
Publicado: (2016)

PRIM2 Promotes Cell Cycle and Tumor Progression in p53-Mutant Lung Cancer
por: Wang, Taoyuan, et al.
Publicado: (2022)

Corrigendum: The Identification of Two RNA Modification Patterns and Tumor Microenvironment Infiltration Characterization of Lung Adenocarcinoma
por: He, Wan, et al.
Publicado: (2022)

Tumor-infiltrating lymphocyte: features and prognosis of lymphocytes infiltration on colorectal cancer
por: Qin, Miao, et al.
Publicado: (2023)

p53 and its mutants in tumor cell migration and invasion
por: Muller, Patricia A. J., et al.
Publicado: (2011)

Identification, validation, and targeting of the mutant p53-PARP-MCM chromatin axis in triple negative breast cancer
por: Qiu, Wei-Gang, et al.
Publicado: (2017)

p53’s Extended Reach: The Mutant p53 Secretome
por: Pavlakis, Evangelos, et al.
Publicado: (2020)

Identification of prognostic tumor-infiltrating immune cells in endometrial adenocarcinoma
por: Pan, Xin-Bin, et al.
Publicado: (2021)

The difference and relationship of CD4+ and CD8+ tumour infiltrating lymphocytes in lung adenocarcinoma
por: Zhang, Chaoting, et al.
Publicado: (2019)

Identification of a pyroptosis-related lncRNA signature in the regulation of prognosis, metabolism signals and immune infiltration in lung adenocarcinoma
por: Zhou, Shuyi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_m46r2k2ammbvallsagh4pu1gka