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Long non-coding RNA CHRF accelerates LPS-induced acute lung injury through microRNA-146a/Notch1 axis

BACKGROUND: The present study sought to investigate the regulatory role of the long non-coding RNA (lncRNA) cardiac hypertrophy-related factor (CHRF) in a mouse model of acute lung injury (ALI) and in primary mouse pulmonary microvascular endothelial cells (MPVECs) treated with lipopolysaccharide (L...

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Detalles Bibliográficos
Autores principales: Luo, Shu, Ding, Xuefeng, Zhao, Shiqiao, Mou, Tianyi, Li, Ruixiu, Cao, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422153/
https://www.ncbi.nlm.nih.gov/pubmed/34532436
http://dx.doi.org/10.21037/atm-21-3064