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Current Management and Image Review of Skull Base Chordoma: What the Radiologist Needs to Know

Chordomas of the skull-base are typically slow-growing, notochord-derived tumors that most commonly originate along the clivus. Skull base chordoma is treated with surgery and radiotherapy. Local recurrence approaches 50% at 10 years. Radiologists play a critical role in diagnosis, treatment plannin...

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Autores principales: Soule, Erik, Baig, Saif, Fiester, Peter, Holtzman, Adam, Rutenberg, Michael, Tavanaiepour, Daryoush, Rao, Dinesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422542/
https://www.ncbi.nlm.nih.gov/pubmed/34513210
http://dx.doi.org/10.25259/JCIS_139_2021
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author Soule, Erik
Baig, Saif
Fiester, Peter
Holtzman, Adam
Rutenberg, Michael
Tavanaiepour, Daryoush
Rao, Dinesh
author_facet Soule, Erik
Baig, Saif
Fiester, Peter
Holtzman, Adam
Rutenberg, Michael
Tavanaiepour, Daryoush
Rao, Dinesh
author_sort Soule, Erik
collection PubMed
description Chordomas of the skull-base are typically slow-growing, notochord-derived tumors that most commonly originate along the clivus. Skull base chordoma is treated with surgery and radiotherapy. Local recurrence approaches 50% at 10 years. Radiologists play a critical role in diagnosis, treatment planning, and follow-up. Surgeons and radiation oncologists rely on radiologists for pre-operative delineation of tumor and adjacent anatomy, identification of post-treatment changes and disease recurrence, and radiation treatment effects. This review provides an overview of clinical characteristics, surgical anatomy, indications for radiotherapy, identification of treatment complications, and patterns of disease recurrence for radiologists to provide value in the management of these lesions.
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spelling pubmed-84225422021-09-09 Current Management and Image Review of Skull Base Chordoma: What the Radiologist Needs to Know Soule, Erik Baig, Saif Fiester, Peter Holtzman, Adam Rutenberg, Michael Tavanaiepour, Daryoush Rao, Dinesh J Clin Imaging Sci Review Article Chordomas of the skull-base are typically slow-growing, notochord-derived tumors that most commonly originate along the clivus. Skull base chordoma is treated with surgery and radiotherapy. Local recurrence approaches 50% at 10 years. Radiologists play a critical role in diagnosis, treatment planning, and follow-up. Surgeons and radiation oncologists rely on radiologists for pre-operative delineation of tumor and adjacent anatomy, identification of post-treatment changes and disease recurrence, and radiation treatment effects. This review provides an overview of clinical characteristics, surgical anatomy, indications for radiotherapy, identification of treatment complications, and patterns of disease recurrence for radiologists to provide value in the management of these lesions. Scientific Scholar 2021-08-30 /pmc/articles/PMC8422542/ /pubmed/34513210 http://dx.doi.org/10.25259/JCIS_139_2021 Text en © 2021 Published by Scientific Scholar on behalf of Journal of Clinical Imaging Science https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Review Article
Soule, Erik
Baig, Saif
Fiester, Peter
Holtzman, Adam
Rutenberg, Michael
Tavanaiepour, Daryoush
Rao, Dinesh
Current Management and Image Review of Skull Base Chordoma: What the Radiologist Needs to Know
title Current Management and Image Review of Skull Base Chordoma: What the Radiologist Needs to Know
title_full Current Management and Image Review of Skull Base Chordoma: What the Radiologist Needs to Know
title_fullStr Current Management and Image Review of Skull Base Chordoma: What the Radiologist Needs to Know
title_full_unstemmed Current Management and Image Review of Skull Base Chordoma: What the Radiologist Needs to Know
title_short Current Management and Image Review of Skull Base Chordoma: What the Radiologist Needs to Know
title_sort current management and image review of skull base chordoma: what the radiologist needs to know
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422542/
https://www.ncbi.nlm.nih.gov/pubmed/34513210
http://dx.doi.org/10.25259/JCIS_139_2021
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