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The Role of Amyloid-Beta and Tau in the Early Pathogenesis of Alzheimer’s Disease
The abnormal accumulation of amyloid-β (Aβ) and neurofibrillary tangles (NFTs) containing phosphorylated tau proteins are the main histopathological feature of Alzheimer’s disease (AD). Synaptic damage and loss are earlier events than amyloid plaques and NFTs in AD progress and best correlate with c...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422899/ https://www.ncbi.nlm.nih.gov/pubmed/34471085 http://dx.doi.org/10.12659/MSM.933084 |