Cargando…

The Role of Amyloid-Beta and Tau in the Early Pathogenesis of Alzheimer’s Disease

The abnormal accumulation of amyloid-β (Aβ) and neurofibrillary tangles (NFTs) containing phosphorylated tau proteins are the main histopathological feature of Alzheimer’s disease (AD). Synaptic damage and loss are earlier events than amyloid plaques and NFTs in AD progress and best correlate with c...

Descripción completa

Detalles Bibliográficos
Autores principales: Yin, Xiaomin, Qiu, Yanyan, Zhao, Chenhao, Zhou, Zheng, Bao, Junze, Qian, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422899/
https://www.ncbi.nlm.nih.gov/pubmed/34471085
http://dx.doi.org/10.12659/MSM.933084