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Validation of a Triplex Pharmacokinetic Assay for Simultaneous Quantitation of HIV-1 Broadly Neutralizing Antibodies PGT121, PGDM1400, and VRC07-523-LS

The outcome of the recent Antibody Mediated Prevention (AMP) trials that tested infusion of the broadly neutralizing antibody (bnAb) VRC01 provides proof of concept for blocking infection from sensitive HIV-1 strains. These results also open up the possibility that triple combinations of bnAbs such...

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Detalles Bibliográficos
Autores principales:	Wesley, Martina S., Chiong, Kelvin T., Seaton, Kelly E., Arocena, Christine A., Sawant, Sheetal, Hare, Jonathan, Hernandez, Kasey, Rojas, Michelle, Heptinstall, Jack, Beaumont, David, Crisafi, Katherine, Nkolola, Joseph, Barouch, Dan H., Sarzotti-Kelsoe, Marcella, Tomaras, Georgia D., Yates, Nicole L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422903/ https://www.ncbi.nlm.nih.gov/pubmed/34504492 http://dx.doi.org/10.3389/fimmu.2021.709994

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