A Murine Model of Mycobacterium kansasii Infection Reproducing Necrotic Lung Pathology Reveals Considerable Heterogeneity in Virulence of Clinical Isolates

Among non-tuberculous mycobacteria, Mycobacterium kansasii is one of the most pathogenic, able to cause pulmonary disease indistinguishable from tuberculosis in immunocompetent susceptible adults. The lack of animal models that reproduce human-like lung disease, associated with the necrotic lung pat...

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Detalles Bibliográficos
Autores principales: Mussi, Vinicius O., Simão, Thatiana L. B. V., Almeida, Fabrício M., Machado, Edson, de Carvalho, Luciana D., Calixto, Sanderson D., Sales, Guilherme A. M., Carvalho, Eulógio C. Q., Vasconcellos, Sidra E. G., Catanho, Marcos, Suffys, Philip N., Lasunskaia, Elena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422904/
https://www.ncbi.nlm.nih.gov/pubmed/34504483
http://dx.doi.org/10.3389/fmicb.2021.718477

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