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Differential diagnosis of COVID-19 at the chest computed tomography scan: A review with special focus on cancer patients

BACKGROUND: Given the several radiological features shared by coronavirus disease 2019 pneumonia and other infective or non-infective diseases with lung involvement, the differential diagnosis is often tricky, and no unequivocal tool exists to help the radiologist in the proper diagnosis. Computed t...

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Autores principales: Perrone, Fabiana, Balbi, Maurizio, Casartelli, Chiara, Buti, Sebastiano, Milanese, Gianluca, Sverzellati, Nicola, Bersanelli, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422906/
https://www.ncbi.nlm.nih.gov/pubmed/34567434
http://dx.doi.org/10.4329/wjr.v13.i8.243
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author Perrone, Fabiana
Balbi, Maurizio
Casartelli, Chiara
Buti, Sebastiano
Milanese, Gianluca
Sverzellati, Nicola
Bersanelli, Melissa
author_facet Perrone, Fabiana
Balbi, Maurizio
Casartelli, Chiara
Buti, Sebastiano
Milanese, Gianluca
Sverzellati, Nicola
Bersanelli, Melissa
author_sort Perrone, Fabiana
collection PubMed
description BACKGROUND: Given the several radiological features shared by coronavirus disease 2019 pneumonia and other infective or non-infective diseases with lung involvement, the differential diagnosis is often tricky, and no unequivocal tool exists to help the radiologist in the proper diagnosis. Computed tomography is considered the gold standard in detecting pulmonary illness caused by severe acute respiratory syndrome coronavirus 2. AIM: To conduct a systematic review including the available studies evaluating computed tomography similarities and discrepancies between coronavirus disease 2019 pneumonia and other pulmonary illness, then providing a discussion focus on cancer patients. METHODS: Using pertinent keywords, we performed a systematic review using PubMed to select relevant studies published until October 30, 2020. RESULTS: Of the identified 133 studies, 18 were eligible and included in this review. CONCLUSION: Ground-glass opacity and consolidations are the most common computed tomography lesions in coronavirus disease 2019 pneumonia and other respiratory diseases. Only two studies included cancer patients, and the differential diagnosis with early lung cancer and radiation pneumonitis was performed. A single lesion associated with pleural effusion and lymphadenopathies in lung cancer and the onset of the lesions in the radiation field in the case of radiation pneumonitis allowed the differential diagnosis. Nevertheless, the studies were heterogeneous, and the type and prevalence of lesions, distributions, morphology, evolution, and additional signs, together with epidemiological, clinical, and laboratory findings, are crucial to help in the differential diagnosis.
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spelling pubmed-84229062021-09-24 Differential diagnosis of COVID-19 at the chest computed tomography scan: A review with special focus on cancer patients Perrone, Fabiana Balbi, Maurizio Casartelli, Chiara Buti, Sebastiano Milanese, Gianluca Sverzellati, Nicola Bersanelli, Melissa World J Radiol Systematic Reviews BACKGROUND: Given the several radiological features shared by coronavirus disease 2019 pneumonia and other infective or non-infective diseases with lung involvement, the differential diagnosis is often tricky, and no unequivocal tool exists to help the radiologist in the proper diagnosis. Computed tomography is considered the gold standard in detecting pulmonary illness caused by severe acute respiratory syndrome coronavirus 2. AIM: To conduct a systematic review including the available studies evaluating computed tomography similarities and discrepancies between coronavirus disease 2019 pneumonia and other pulmonary illness, then providing a discussion focus on cancer patients. METHODS: Using pertinent keywords, we performed a systematic review using PubMed to select relevant studies published until October 30, 2020. RESULTS: Of the identified 133 studies, 18 were eligible and included in this review. CONCLUSION: Ground-glass opacity and consolidations are the most common computed tomography lesions in coronavirus disease 2019 pneumonia and other respiratory diseases. Only two studies included cancer patients, and the differential diagnosis with early lung cancer and radiation pneumonitis was performed. A single lesion associated with pleural effusion and lymphadenopathies in lung cancer and the onset of the lesions in the radiation field in the case of radiation pneumonitis allowed the differential diagnosis. Nevertheless, the studies were heterogeneous, and the type and prevalence of lesions, distributions, morphology, evolution, and additional signs, together with epidemiological, clinical, and laboratory findings, are crucial to help in the differential diagnosis. Baishideng Publishing Group Inc 2021-08-28 2021-08-28 /pmc/articles/PMC8422906/ /pubmed/34567434 http://dx.doi.org/10.4329/wjr.v13.i8.243 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Systematic Reviews
Perrone, Fabiana
Balbi, Maurizio
Casartelli, Chiara
Buti, Sebastiano
Milanese, Gianluca
Sverzellati, Nicola
Bersanelli, Melissa
Differential diagnosis of COVID-19 at the chest computed tomography scan: A review with special focus on cancer patients
title Differential diagnosis of COVID-19 at the chest computed tomography scan: A review with special focus on cancer patients
title_full Differential diagnosis of COVID-19 at the chest computed tomography scan: A review with special focus on cancer patients
title_fullStr Differential diagnosis of COVID-19 at the chest computed tomography scan: A review with special focus on cancer patients
title_full_unstemmed Differential diagnosis of COVID-19 at the chest computed tomography scan: A review with special focus on cancer patients
title_short Differential diagnosis of COVID-19 at the chest computed tomography scan: A review with special focus on cancer patients
title_sort differential diagnosis of covid-19 at the chest computed tomography scan: a review with special focus on cancer patients
topic Systematic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422906/
https://www.ncbi.nlm.nih.gov/pubmed/34567434
http://dx.doi.org/10.4329/wjr.v13.i8.243
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