SACRED: Effect of simvastatin on hepatic decompensation and death in subjects with high-risk compensated cirrhosis: Statins and Cirrhosis: Reducing Events of Decompensation

BACKGROUND/AIMS: The development of decompensation in cirrhosis demarcates a marked change in the natural history of chronic liver disease. HMG-CoA reductase inhibitors (statins) exert pleiotropic effects that reduce inflammation and fibrosis as well as improve vascular reactivity. Retrospective stu...

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Detalles Bibliográficos
Autores principales: Kaplan, David E., Mehta, Rajni, Garcia-Tsao, Guadalupe, Albrecht, Jeffrey, Aytaman, Ayse, Baffy, Gyorgy, Bajaj, Jasmohan, Hernaez, Ruben, Hunt, Kristel, Ioannou, George, Johnson, Kay, Kanwal, Fasiha, Lee, Tae-Hoon, Monto, Alexander, Pandya, Prashant, Schaubel, Douglas, Taddei, Tamar H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8422958/
https://www.ncbi.nlm.nih.gov/pubmed/33771685
http://dx.doi.org/10.1016/j.cct.2021.106367

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